Henry L. Paulson, M.D., Ph.D.

Causes and treatment of age-related neurodegenerative diseases Lucile Groff Professor of Neurology for Alzheimer’s Disease and Related Disorders Director of the Michigan Alzheimer’s Disease Center Dr. Paulson’s research and clinical interests concern the causes and treatment of age-related neuro degenerative diseases, with a focus on hereditary ataxias, Alzheimer’s disease, and frontotemporal dementia. His laboratory investigates the mechanisms underlying degenerative brain diseases…

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Jack Parent, M.D.

Finding novel therapies for epilepsy Professor, Neurology Director, Neurodevelopment and Regeneration Laboratory Co-director, Comprehensive Epilepsy Center Dr. Parent’s clinical interests are focused on helping patients with brain anomalies caused by injury or neurologic conditions. Using neural stem cells to model genetic neurological disorders, study the mechanisms of brain development, and screen for precision therapies, his ultimate goals are…

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Thomas Gardner, M.D., M.S.

Seeking to prevent and cure eye damage caused by diabetes Healthy Eyes Taubman Scholar Professor, Ophthalmology and Visual Sciences Professor, Molecular & Integrative Physiology Director, Juvenile Diabetes Research Foundation Diabetic Retinopathy Center The overall goal of Dr. Gardner’s clinical care and research is to help people with diabetes maintain good vision. By combining evaluations of…

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Sharlene Day, M.D.

Understanding the disease mechanisms of hypertrophic cardiomyopathy Associate Professor, Internal Medicine Dr. Day is a cardiologist at U-M and her research focuses on hypertrophic cardiomyopathy, the most common inherited heart condition which is associated with sudden cardiac death and heart failure. By studying mutations that cause this condition, her work is improving our understanding of disease mechanisms…

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Kathleen Collins, M.D., Ph.D.

Improving therapies for HIV Professor of Internal Medicine Dr. Collins has focused her clinical and research career on improving therapies for HIV, the virus that causes AIDS. To this end, her studies are enhancing our understanding of the molecular mechanisms of viral persistence within long-lived cells and supporting the development of drugs that will inhibit these pathways…

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Valerie P. Opipari, MD

Discovering Treatments for Childhood Cancers Ravitz Professor and Chair, Department of Pediatric and Communicable Diseases Pediatrician-in-Chief Director of the Taubman Institute’s Neuroblastoma Research Program Dr. Opipari heads the Pediatrics Department at U-M. Her research and clinical interests focus on the pediatricsolid tumor, neuroblastoma, and she is devoted to uncovering the underlying mechanisms in the development…

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John Carethers, M.D.

The role of inflammation in colon cancer John G. Searle Professor Chair, Department of Internal Medicine Dr. Carethers’ clinical interests are in hereditary colon cancer syndromes, and in the laboratory, he is studying both tumor genetics and how inflammation impacts the pathogenesis of gastrointestinal cancers in order toidentify new targets and approaches to improve the…

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Frank C. Brosius III, M.D.

Protecting Kidney Cells from Diabetic Disease Professor of Internal Medicine and Molecular and Integrative Physiology Division Chief of Nephrology Dr. Brosius is expert in the clinical care of individuals with kidney diseases. In his laboratory, he is identifying thecritical pathways that cause progressive kidney disease in diabetes so that therapies that halt the progression ofthis…

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Charles F. Burant, M.D., Ph.D.

New Approaches in Understanding and Treating Obesity Robert C. and Veronica Atkins Professor of Metabolism Professor of Internal Medicine and Molecular and Integrative Physiology Director, U-M Metabolomics and Obesity Center Dr. Burant’s clinical and research interests are centered on metabolic diseases, including obesity, type 2 diabetes,and related metabolic disorders. His research has improved our understanding…

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Nicholas Boulis, M.D.

Developing Cellular and Molecular Therapies for the Nervous System Adjunct Associate Professor of Neurology at U-M Associate Professor of Neurosurgery at Emory University As a neurosurgeon, Dr. Boulis has pioneered numerous innovative approaches to deliver gene and cellulartherapies to the nervous system to keep neurons healthy in the face of neurodegenerative and functional diseasesof the…

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