The immunopathology of multiple sclerosis Holtom-Garrett Professor of Neurology Director, University of Michigan Multiple Sclerosis Center Director, Holtom-Garrett Program in Neuroimmunology Dr. Segal’s clinical and research interests involve understanding the pathogenesis of multiple sclerosis, aninflammatory disease of the nervous system. By understanding how immune factors and/or cells contribute to the disease, he expects to be able to predict…
DetailsSpeeding recovery after muscle and joint injuries Frances and Kenneth Eisenberg Emerging Scholar Assistant Professor, Sports Medicine, Shoulder, & Hip Preservation Surgery Director, Sports Medicine Research Program, U-M MedSport In addition to helping patients as an orthopaedic surgeon, Dr. Bedi is using cellular and molecular studies on human tissues to fuel discoveries that may help speed…
DetailsUnderstanding the role of inflammation in graft-versus-host disease after bone-marrow transplant. Moshe Talpaz Professor of Translational Oncology Dr. Reddy’s clinical interests focus on graft-versus-host disease (GVHD), a severe and life-threatening complication that can result following bone marrow transplantation to cure hematologic cancers. His efforts in the laboratory have enhanced our understanding GVHD immunobiology, and the resulting clinical…
DetailsCauses and treatment of age-related neurodegenerative diseases Lucile Groff Professor of Neurology for Alzheimer’s Disease and Related Disorders Director of the Michigan Alzheimer’s Disease Center Dr. Paulson’s research and clinical interests concern the causes and treatment of age-related neuro degenerative diseases, with a focus on hereditary ataxias, Alzheimer’s disease, and frontotemporal dementia. His laboratory investigates the mechanisms underlying degenerative brain diseases…
DetailsFinding novel therapies for epilepsy Professor, Neurology Director, Neurodevelopment and Regeneration Laboratory Co-director, Comprehensive Epilepsy Center Dr. Parent’s clinical interests are focused on helping patients with brain anomalies caused by injury or neurologic conditions. Using neural stem cells to model genetic neurological disorders, study the mechanisms of brain development, and screen for precision therapies, his ultimate goals are…
DetailsSeeking to prevent and cure eye damage caused by diabetes Healthy Eyes Taubman Scholar Professor, Ophthalmology and Visual Sciences Professor, Molecular & Integrative Physiology Director, Juvenile Diabetes Research Foundation Diabetic Retinopathy Center The overall goal of Dr. Gardner’s clinical care and research is to help people with diabetes maintain good vision. By combining evaluations of…
DetailsUnderstanding the disease mechanisms of hypertrophic cardiomyopathy Associate Professor, Internal Medicine Dr. Day is a cardiologist at U-M and her research focuses on hypertrophic cardiomyopathy, the most common inherited heart condition which is associated with sudden cardiac death and heart failure. By studying mutations that cause this condition, her work is improving our understanding of disease mechanisms…
DetailsImproving therapies for HIV Professor of Internal Medicine Dr. Collins has focused her clinical and research career on improving therapies for HIV, the virus that causes AIDS. To this end, her studies are enhancing our understanding of the molecular mechanisms of viral persistence within long-lived cells and supporting the development of drugs that will inhibit these pathways…
DetailsDiscovering Treatments for Childhood Cancers Ravitz Professor and Chair, Department of Pediatric and Communicable Diseases Pediatrician-in-Chief Director of the Taubman Institute’s Neuroblastoma Research Program Dr. Opipari heads the Pediatrics Department at U-M. Her research and clinical interests focus on the pediatricsolid tumor, neuroblastoma, and she is devoted to uncovering the underlying mechanisms in the development…
DetailsThe role of inflammation in colon cancer John G. Searle Professor Chair, Department of Internal Medicine Dr. Carethers’ clinical interests are in hereditary colon cancer syndromes, and in the laboratory, he is studying both tumor genetics and how inflammation impacts the pathogenesis of gastrointestinal cancers in order toidentify new targets and approaches to improve the…
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